List of articles in "Drug" category - Page 69

O-2372 is an analgesic cannabinoid derivative created by Organix Inc. for use in scientific research. It has high affinity for both CB1 and CB2 receptors with Ki values of 1.3nM […]

O-1812 is an eicosanoid derivative related to anandamide that acts as a potent and highly selective agonist for the cannabinoid receptor CB1 with a Ki of 3.4nM at CB1 and […]

Betacetylmethadol is a synthetic opioid. It is a diastereoisomer of alphacetylmethadol (as well as levacetylmethadol). In the United States betacetylmethadol is a Schedule I drug under the Controlled Substances Act.

Not to be confused with acetylmethadol.Alphacetylmethadol (INN) or α-acetylmethadol (AAM) is a synthetic opioid analgesic. Its levorotary enantiomer levacetylmethadol is an FDA-approved treatment for opioid addiction. Alphacetylmethadol is very similar […]

Ro60-0213 (Org 35032) is a drug developed by Hoffmann–La Roche which acts as a potent and selective agonist for the 5-HT2C serotonin receptor with more than 100x selectivity over other […]

Prinomastat (AG-3340) is a matrix metalloprotease (MMP) inhibitor with specific selectivity for MMPs 2 3 9 13 and 14. Investigations have been carried out to determine whether the inhibition of […]

Ponatinib (trade name Iclusig previously AP24534) is an Food and Drug Administration–approved oral drug candidate developed by ARIAD Pharmaceuticals for the treatment of chronic myeloid leukemia (CML) and Philadelphia chromosome–positive […]

Cabozantinib (marketed under the tradename Cometriq formerly known as XL184) is a small molecule inhibitor of the tyrosine kinases c-Met and VEGFR2 and has been shown to reduce tumor growth […]

Cymserine is a drug related to physostigmine which acts as a reversible cholinesterase inhibitor with moderate selectivity (15x) for the plasma cholinesterase enzyme butyrylcholinesterase and relatively weaker inhibition of the […]

Spiraprilat is the active metabolite of Spirapril.