S-Ethylisothiouronium diethylphosphate (brand name Difetur) is an S-alkylisothiouronium derivative used as an antihypotensive drug. The S-alkylisothiouronium compounds are used in processes of treating acute hypotension which may result for example […]
List of articles in "Drug" category - Page 66
AFDX-384
AFDX-384 (BIBN-161) is a drug which acts as a selective antagonist of the muscarinic acetylcholine receptors with selectivity for the M2 and M4 subtypes. It is used mainly for mapping […]
FG-8205
FG-8205 (L-663581) is an imidazobenzodiazepine derivative related to bretazenil which acts as a partial agonist at GABAA receptors with slight selectivity for the α1-containing subtype. In animal tests it has […]
PD-0298029
PD-0298029 is a drug which acts as a selective antagonist for the muscarinic acetylcholine receptor M4. It was developed for the treatment of Parkinson’s disease but poor bioavailability and rapid […]
VU-0238429
VU-0238429 is a drug which acts as a selective positive allosteric modulator for the muscarinic acetylcholine receptor M5. It was the first selective ligand developed for the M5 subtype and […]
PD-102807
PD-102807 is a drug which acts as a selective antagonist for the muscarinic acetylcholine receptor M4. It is used in scientific research for studying the effects of the different muscarinic […]
Varespladib
Varespladib is an inhibitor of the IIa V and X isoforms of secretory phospholipase A2 (sPLA2). The molecule acts as an anti-inflammatory agent by disrupting the first step of the […]
Varespladib methyl
Varespladib methyl (also known as A-002 formerly LY333013 and S-3013) is a secretory phospholipase A2 (sPLA2) inhibitor formerly under development by Anthera Pharmaceuticals as a treatment for acute coronary syndrome […]
Mefway (18F)
Mefway is a 5-HT1A receptor antagonist used in medical research usually in the form of mefway (18F) as a positron emission tomography (PET) radiotracer.
Amitifadine
Amitifadine (am-i-TIF-a-deen) also known as DOV-21947 or EB-1010 is an antidepressant drug being developed by Euthymics Bioscience Inc. It is a so-called triple reuptake inhibitor (TRI) or serotonin-norepinephrine-dopamine reuptake inhibitor […]