List of articles in "Drug" category - Page 68

R-30490 is an opioid analgesic drug related to the highly potent animal tranquilizer carfentanil and with only slightly lower potency. It was first synthesised by a team of chemists at […]

Furafylline is a methylxanthine derivative that was introduced in hope of being a long-acting replacement for theophylline in the treatment of asthma. It is an inhibitor of CYP1A2.

N-Methylcarfentanil (R-32395) is an opioid analgesic drug related to the highly potent animal tranquilizer carfentanil but several thousand times weaker being only slightly stronger than morphine. It was first synthesised […]

N-Phenethylnordesomorphine is an opiate analgesic drug derived from desomorphine by replacing the N-methyl group with β-phenethyl. Since desomorphine is already around eight times more potent than morphine the additional boost […]

3-Methoxymorphinan is a dextromethorphan metabolite that has been shown to produce local anesthetic effects. It is metabolized in the liver by the enzyme CYP3A4.

Vismodegib (trade name Erivedge) is a drug for the treatment of basal-cell carcinoma (BCC). The approval of vismodegib on January 30 2012 represents the first Hedgehog signaling pathway targeting agent […]

AM-1220 is a drug that acts as a potent and moderately selective agonist for the cannabinoid receptor CB1 with around 19x selectivity for CB1 over the related CB2 receptor. It […]

The drug combination alfatradiol/dexamethasone (trade name Ell-Cranell dexa in Germany) is used topically for the treatment of mild to moderate androgenic alopecia (hair loss) in younger women.

Melanocyte-inhibiting factor (also known as Pro-Leu-Gly-NH2 Melanostatin MSH release-inhibiting hormone or MIF-1) is an endogenous peptide fragment derived from cleavage of the hormone oxytocin but having generally different actions in […]

Atagabalin (PD-0200390) is a drug developed by Pfizer and related to gabapentin which similarly binds to the α2δ calcium channels (1 and 2). It is under development as a treatment […]