List of articles in "Drug" category - Page 41

RO-4491533 is a drug developed by Hoffmann-La Roche which acts as a potent and selective negative allosteric modulator for group II of the metabotropic glutamate receptors (mGluR2/3) being equipotent at […]

EPPTB (RO-5212773) is a drug developed by Hoffmann-La Roche which acts as a potent and selective antagonist for the trace amine-associated receptor 1 with no significant activity at other targets. […]

RO-5166017 is a drug developed by Hoffmann-La Roche which acts as a potent and selective agonist for the trace amine-associated receptor 1 with no significant activity at other targets.

Thiotetrabarbital (INN; Thionarcex) is a drug which is a short-acting barbiturate derivative that is used as an anesthetic. It has been used in veterinary medicine.

Edivoxetine (INN; LY-2216684) is a drug which acts as a selective norepinephrine reuptake inhibitor and is currently under development by Eli Lilly as an antidepressant and as a treatment for […]

Lometraline (INN; CP-14368) is a drug which is an aminotetralin derivative. A structural modification of the investigative neuroleptic pinoxepin lometraline was originally patented by Pfizer as an antipsychotic tranquilizer and […]

Tinabinol (INN; SP-119) is a synthetic cannabinoid drug and analogue of dronabinol which was patented as an antihypertensive but was never marketed.

Gestaclone (INN USAN; SH-1040) is a drug which is a steroidal progestin that was never marketed.

Metkefamide (INN; LY-127623) or metkephamid acetate (USAN) but most frequently referred to simply as metkephamid is a synthetic opioid pentapeptide and derivative of [Met]enkephalin with the amino acid sequence Tyr-D-Ala-Gly-Phe-(N-Me)-Met-NH2.

Frakefamide (INN) is a synthetic fluorinated opioid tetrapeptide with the amino acid sequence Tyr-D-Ala-(p-F)Phe-Phe-NH2 which acts as a peripherally-specific selective μ-opioid receptor agonist.