Tedalinab (GRC-10693) is a drug developed by Glenmark Pharmaceuticals for the treatment of osteoarthritis and neuropathic pain which acts as a potent and selective cannabinoid CB2 receptor agonist. It has […]
List of articles in "Drug" category - Page 40
Pingyangmycin
Pingyangmycin (also known as Bleomycin A5) is an antitumor glycopeptide antibiotic belongs to bleomycin which is produced by Streptomyces verticillus var. pingyangensis n.sp. a variety of Streptomyces verticillus.
Lidanserin
Lidanserin (INN; ZK-33839) is a drug which acts as a combined 5-HT2A and α1-adrenergic receptor antagonist. It was developed as an antihypertensive agent but was never marketed.
Iferanserin
Iferanserin (INN; VEN-309) is a drug which acts as a selective 5-HT2A receptor antagonist. It is under development as an intra-rectal formulation for the treatment of hemorrhoid disease and as […]
Tropanserin
Tropanserin (INN; MDL-72422) is a drug which acts as a potent and selective 5-HT3 receptor antagonist. It was investigated in clinical trials for the treatment of migraine in the 1980s […]
Glemanserin
Glemanserin (INN; MDL-11939) is a drug which acts as a potent and selective 5-HT2A receptor antagonist. The first truly selective 5-HT2A ligand to be discovered glemanserin resulted in the development […]
6-Chloro-5-ethoxy-N-(pyridin-2-yl)indoline-1-carboxamide
6-Chloro-5-ethoxy-N-(pyridin-2-yl)indoline-1-carboxamide (CEPC) is a drug which acts as a potent and selective antagonist for the serotonin 5-HT2C receptor. In animal studies it was found to potentiate the conditioned place preference […]
O-Phenyl-3-iodotyramine
O-Phenyl-3-iodotyramine (O-PIT) is a drug which acts as a selective agonist for the trace amine-associated receptor 1. It has reasonable selectivity for TAAR1 but relatively low potency and is rapidly […]
RG7351
RG7351 is a drug which acts as a presumably selective partial agonist of the trace amine-associated receptor 1 (TAAR1). It is currently under early stage development by Hoffmann–La Roche for […]
LASSBio-881
LASSBio-881 is a drug which acts as both a non-selective partial agonist of the CB1 and CB2 cannabinoid receptors and also as an antagonist of the TRPV1 receptor as well […]