Naldemedine (INN USAN; S-297995) is a peripherally-selective μ-opioid receptor antagonist under development by Shionogi for the treatment of opioid-induced adverse effects including constipation nausea and vomiting. Clinical studies have thus […]
List of articles in "Drug" category - Page 39
Ketorfanol
Ketorfanol (INN USAN; SBW-22) or ketorphanol is an opioid analgesic of the morphinan series that was never marketed.
Nalorphine dinicotinate
Nalorphine dinicotinate (Nimelan) or N-allylnormorphine dinicotinate also known as niconalorphine is a semisynthetic mixed opioid agonist-antagonist used as a narcotic antagonist.It is the 36-dinicotinate ester of nalorphine.
Nalmexone
Nalmexone (INN; EN-1620A UM-592) or nalmexone hydrochloride (USAN) is a semisynthetic mixed opioid agonist-antagonist with analgesic and narcotic antagonist properties that was never marketed. In clinical studies it was found […]
Axomadol
Axomadol (INN USAN; EN3324) is a synthetic centrally-acting analgesic which was under investigation by Endo Pharmaceuticals in collaboration with Grünenthal for the treatment of chronic moderate to severe lower back […]
Noracymethadol
Noracymethadol (INN) is a synthetic opioid analgesic related to methadone that was never marketed. In a clinical trial of postpartum patients it was reported to produce analgesia comparable to that […]
Norpipanone
Norpipanone (INN BAN; Hexalgon) is an opioid analgesic related to methadone which was developed in Germany and distributed in Hungary Argentina and other countries. It had originally not been under […]
Alimadol
Alimadol(INN; A-4020) is an opioid analgesic related to methadone that was never marketed.
GRN-529
GRN-529 is a research drug that was developed by Wyeth as a negative allosteric modulator of the metabotropic glutamate receptor 5 (mGluR5).A study conducted by Pfizer found that GRN-529 reduced […]
Menabitan
Menabitan (INN; SP-204) or menabitan hydrochloride (USAN) is a synthetic drug which acts as a potent cannabinoid receptor agonist. It is closely related to natural cannabinoids of the tetrahydrocannabinol (THC) […]