Tags: Drug.
Lometraline (INN; CP-14368) is a drug which is an aminotetralin derivative. A structural modification of the investigative neuroleptic pinoxepin lometraline was originally patented by Pfizer as an antipsychotic tranquilizer and antiparkinsonian agent (likely as an anticholinergic). However it was instead later studied as a potential antidepressant and/or anxiolytic agent but clinical studies revealed no psychoactivity at the doses used and further investigation was suspended.