PF-04457845 is a potent and exquisitely selective inhibitor of the enzyme fatty acid amide hydrolase (FAAH) with an IC50 of 7.2nM and both analgesic and antiinflammatory effects in animal studies […]
List of articles in "Drug" category - Page 36
LBP-1 (drug)
LBP-1 is a drug originally developed by Organon for the treatment of neuropathic pain and subsequently further developed by Merck after they acquired Organon’s patents following their merger with Schering-Plough. […]
Radequinil
Radequinil (INN; AC-3933) is a cognitive enhancer which acts as a partial inverse agonist of the benzodiazepine site of the GABAA receptor. It was under development by Dainippon Sumitomo Pharma […]
Nitecapone
Nitecapone (INN; OR-462) is a drug which acts as a selective inhibitor of the enzyme catechol O-methyl transferase (COMT). It was patented as an antiparkinsonian agent but was never marketed.
Prinaberel
Prinaberel (INN USAN; ERB-041) is a drug which acts as a highly selective agonist of the ERβ subtype of the estrogen receptor. It is used in scientific research to elucidate […]
Estradiol dipropionate
Estradiol dipropionate (BAN JAN; brand names Agofollin Diovocyclin Progynon-DP others) is a synthetic ester specifically the 317-dipropanoyl ester of the natural estrogen estradiol. Alongside estradiol benzoate estradiol dipropionate was one […]
Estradiol undecylate
Estradiol undecylate (INN USAN; brand names Delestrec Depogin Primogyn Depot Progynon Depot others) is a synthetic ester specifically the 17-undecanoyl ester of the natural estrogen estradiol. It has been in […]
Plomestane
Plomestane (INN USAN; MDL-18962) also referred to as propargylestrenedione (PED) is a steroidal irreversible aromatase inhibitor which was under development by Marion Merrell Dow/Hoechst Marion Russell (now Hoechst AG) as […]
Minamestane
Minamestane (INN; FCE-24928) is a steroidal aromatase inhibitor which was under development by Farmitalia Carlo Erb as an antineoplastic agent in the mid-1990s but was never marketed.
Carbenzide
Carbenzide (INN) also known as carbazic acid is a hydrazine derivative monoamine oxidase inhibitor (MAOI) antidepressant which was never marketed.