Tags: Drug.
Amitifadine (am-i-TIF-a-deen) also known as DOV-21947 or EB-1010 is an antidepressant drug being developed by Euthymics Bioscience Inc. It is a so-called triple reuptake inhibitor (TRI) or serotonin-norepinephrine-dopamine reuptake inhibitor (SNDRI).It is the (+)-enantiomer of DOV-216303 and its (-)-enantiomer is DOV-102677. Ki values for SERT NET and DAT are 99 nM 262 nM and 213 nM.
