List of articles in "Drug" category - Page 34

NE-100 or 4-methoxy-3-(2-phenylethoxy)-NN-dipropylbenzeneethanamine is a selective sigma-1 receptor antagonist with a reported binding affinity of Ki = 1.03 ± 0.01 nM and more than 205 times selectivity over the sigma-2 […]

PD 144418 or 1236-tetrahydro-5-[3-(4-methylphenyl)-5-isoxazolyl]-1-propylpyridine is a potent and selective ligand for the sigma-1 receptor with a reported binding affinity of Ki = 0.08 ± 0.01 nM and 17 212 times […]

Vorsetuzumab mafodotin (SGN-75) is an antibody-drug conjugate (ADC) directed to the protein CD70 designed for the treatment of cancer. It is a humanized monoclonal antibody vorsetuzumab conjugated with noncleavable monomethyl […]

DPA-713 or NN-diethyl-2-(4-methoxyphenyl)-57-dimethylpyrazolo[15-a]pyrimidine-3-acetamide is a selective ligand for the translocator protein (TSPO).The binding affinity of DPA-713 for TSPO is reported as Ki = 4.7 ± 0.2 nM.DPA-713 has been radiolabelled […]

Clofexamide (or amichlophene) is an antidepressant that was a component of the drug combination clofezone the other being the non-steroidal anti-inflammatory drug (NSAID) phenylbutazone. Clofezone was used to treat joint […]

Baricitinib (formerly INCB28050 LY3009104) is an oral JAK1 and JAK2 inhibitor. Baricitinib is in Phase III development as a potential treatment for rheumatoid arthritis. It is in Phase II development […]

DPA-714 or NN-diethyl-2-[4-(2-fluoroethoxy)phenyl]-57-dimethylpyrazolo[15-a]pyrimidine-3-acetamide is a selective ligand for the translocator protein (TSPO) currently under evaluation for several clinical applications.

Chloroprednisone is a topical glucocorticoid first reported in 1960. It is a chlorinated derivative of prednisone. The acetate ester prodrug chloroprednisone 21-acetate was sold under the brand name Topilan as […]

KM-233 is a drug which is an analogue of Δ8-tetrahydrocannabinol (THC) the less active but more stable isomer of the active component of Cannabis. KM-233 differs from Δ8-THC by the […]

Neamine (neomycin A) is an aminoglycoside antibiotic.