Tags: Protein.
XIAP-associated factor 1 is a protein that in humans is encoded by the XAF1 gene.X-linked inhibitor of apoptosis (XIAP; MIM 300079) is a potent member of the IAP family. All members of this family possess baculoviral IAP (BIR) repeats cysteine-rich domains of approximately 80 amino acids that bind and inhibit caspases (e.g. CASP3; MIM 600636). XIAP has 3 BIR domains and a C-terminal RING zinc finger that possesses E3 ubiquitin ligase (see MIM 601623) activity.