Tags: Drug.
WAY-100135 is a serotonergic drug of the phenylpiperazine family which is used in scientific research. It acts as potent 5-HT1A receptor antagonist and was originally believed to be highly selective but further studies have demonstrated that it also acts as a partial agonist of the 5-HT1D receptor (pKi = 7.58; virtually the same affinity for 5-HT1A) and to a much lesser extent of the 5-HT1B receptor (pKi = 5.82).
