Tags: Drug.

Adhyperforin is a phytochemical found in the members of the plant genus Hypericum including St. John’s Wort. It has a very similar pharmacological profile to hyperforin and acts as a TRPC6 ion channel activator thereby inhibiting the reuptake of various neurotransmitters including serotonin norepinephrine dopamine GABA and glutamate. Adhyperforin is found in St. John’s Wort in levels approximately 1/10 those of hyperforin.

Adhyperforin2DACS.svg
ATC prefix
none
CAS number
143183-63-5
IUPAC name
(1R5S6R7S)-4-Hydroxy-6-methyl-5-(2-methylbutanoyl)-137-tris(3-methyl-2-buten-1-yl)-6-(4-methyl-3-penten-1-yl)bicyclo[3.3.1]non-3-ene-29-dione
PubChem
9963735

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