Tags: Drug.
Tetrahydrobiopterin (BH4 THB trade name Kuvan) or sapropterin (INN) is a naturally occurring essential cofactor of the three aromatic amino acid hydroxylase enzymes used in the degradation of amino acid phenylalanine and in the biosynthesis of the neurotransmitters serotonin (5-hydroxytryptamine 5-HT) melatonin dopamine norepinephrine (noradrenaline) epinephrine (adrenaline) and is a cofactor for the production of nitric oxide (NO) by the nitric oxide synthases.
