Tags: Protein.
Signal-transducing adaptor protein 1 is a protein that in humans is encoded by the STAP1 gene.The protein encoded by this gene functions as a docking protein acting downstream of Tec tyrosine kinase in B cell antigen receptor signaling. The protein is directly phosphorylated by Tec in vitro where it participates in a positive feedback loop increasing Tec activity. A mouse ortholog stem cell adaptor protein 1 shares 83% identity with its human counterpart.