Tags: Protein.
Sperm-associated antigen 8 is a protein that in humans is encoded by the SPAG8 gene.The correlation of anti-sperm antibodies with cases of unexplained infertility implicates a role for these antibodies in blocking fertilization. Improved diagnosis and treatment of immunologic infertility as well as identification of proteins for targeted contraception are dependent on the identification and characterization of relevant sperm antigens.