Tags: Drug.
SKF-81297 is a synthetic drug of the benzazepine chemical class that acts as a selective dopamine D1/D5 receptor full agonist and produces a characteristic stimulant-like pattern of anorexia hyperactivity and self-administration in animals. This profile is shared with several related drugs such as 6-Br-APB and SKF-82958 but not with certain other D1 full agonists such as A-77636 reflecting functional selectivity of D1 activation.
