Tags: Drug.
6-Br-APB is a synthetic compound that acts as a selective D1 agonist with the (R)-enantiomer being a potent full agonist while the (S) enantiomer retains its D1 selectivity but is a weak partial agonist. (R)-6-Br-APB and similar D1-selective full agonists like SKF-81297 and SKF-82958 produce characteristic anorectic effects stereotyped behaviour and self-administration in animals with a similar but not identical profile to that of dopaminergic stimulants such as amphetamine.
