Silibinin (INN) also known as silybin (both from Silybum the generic name of the plant from which it is extracted) is the major active constituent of silymarin a standardized extract of the milk thistle seeds containing a mixture of flavonolignans consisting of silibinin isosilibinin silicristin silidianin and others. Silibinin itself is mixture of two diastereomers silybin A and silybin B in approximately equimolar ratio.
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