Tags: Enzyme.
Serotonin N-acetyltransferase (SNAT) (EC 2.3.1.87) also known as arylalkylamine N-acetyltransferase (AANAT) is an enzyme that is involved in the day/night rhythmic production of melatonin by modification of serotonin. It is in humans encoded by the ~2.5 kb AANAT gene containing four exons located on chromosome 17q25. The gene is translated into a 23 kDa large enzyme. It is well conserved through evolution and the human form of the protein is 80% identical to sheep and rat AANAT.