Tags: Enzyme.
Dihydroorotate dehydrogenase (EC 1.3.3.1) is an enzyme that catalyzes the fourth step in the de novo biosynthesis of pyrimidine. It converts dihydroorotate to orotate: (S)-dihydroorotate + O2 orotate + H2O2 Human dihydroorotate dehydrogenase is a ubiquitous FMN flavoprotein. In bacteria (gene pyrD) it is located on the inner side of the cytosolic membrane.
