Tags: Protein.
Rac GTPase-activating protein 1 is an enzyme that in humans is encoded by the RACGAP1 gene.Rho GTPases control a variety of cellular processes. There are 3 subtypes of Rho GTPases in the Ras superfamily of small G proteins: RHO (see MIM 165370) RAC (see RAC1; MIM 602048) and CDC42 (MIM 116952). GTPase-activating proteins (GAPs) bind activated forms of Rho GTPases and stimulate GTP hydrolysis. Through this catalytic function Rho GAPs negatively regulate Rho-mediated signals.