Tags: Protein.
Polyadenylate-binding protein 1 is a protein that in humans is encoded by the PABPC1 gene.The poly(A)-binding protein (PAB or PABP) which is found complexed to the 3′ poly(A) tail of eukaryotic mRNA is required for poly(A) shortening and translation initiation. In humans the PABPs comprise a small nuclear isoform and a conserved gene family that displays at least 3 functional proteins: PABP1 (PABPC1) inducible PABP (iPABP or PABPC4; MIM 603407) and PABP3 (PABPC3; MIM 604680).