Tags: Protein.
6-phosphofructo-2-kinase/fructose-26-biphosphatase 1 is an enzyme that in humans is encoded by the PFKFB1 gene.This gene encodes a member of the family of bifunctional 6-phosphofructo-2-kinase:fructose-26-biphosphatase enzymes. The enzyme forms a homodimer that catalyzes both the synthesis and degradation of fructose-26-biphosphate using independent catalytic domains. Fructose-26-biphosphate is an activator of the glycolysis pathway and an inhibitor of the gluconeogenesis pathway.