PD-128907 is a drug used in scientific research which acts as a potent and selective agonist for the dopamine D2 and D3 receptors. It is used for studying the role of these receptors in the brain in roles such as inhibitory autoreceptors that act to limit further dopamine release as well as release of other neurotransmitters. In animal studies it has been shown to reduce toxicity from cocaine overdose.
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