Tags: Protein.

Paxillin is a signal transduction adaptor protein discovered in 1990 in the laboratory of Keith Burridge. The C-terminal region of paxillin contains four LIM domains that target paxillin to focal adhesions. It is presumed through a direct association with the cytoplasmic tail of beta-integrin. The N-terminal region of paxillin is rich in protein–protein interaction sites.

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