Tags: Chemical Compound, Chemical Substance.
Nuciferine is an alkaloid found within the plants Nymphaea caerulea and Nelumbo nucifera. It has a profile of action associated with dopamine receptor blockade. It induces sedation hypothermia ptosis and (in higher doses) catalepsy; it inhibits spontaneous motor activity conditioned avoidance response amphetamine toxicity and stereotypy. Nuciferine may also potentiate morphine analgesia. The median lethal dose in mice is 289 mg/kg. It is structurally related to apomorphine.