Tags: Chemical Compound, Chemical Substance.
Morphine-N-oxide (genomorphine) is an active opioid metabolite of morphine. Morphine itself in trials with rats acts 11–22 times more potent than morphine-N-oxide subcutaneously and 39–89 times more potent intraperitoneally. However pretreatment with amiphenazole or tacrine increases the potency of morphine-N-oxide in relation to morphine (intraperitoneally more so than in subcutaneous administration).
