Tags: Chemical Compound, Chemical Substance.

Codeine-6-glucuronide (C6G) is a major active metabolite of codeine and may be responsible for as much as 60% of the analgesic effects of codeine. C6G exhibits decreased immunosuppressive effects compared to codeine. During its metabolism codeine is conjugated with glucuronic acid by the enzyme UDP-Glucuronosyltransferase-2B7 (UGT2B7) to form codeine-6-glucuronide.

Codeine-6-glucuronide.svg
IUPAC name
(5α6α)-3-methoxy-17-methyl-78-didehydro-45-epoxymorphinan-6-yl β-D-glucopyranosiduronic acid

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