Tags: Protein.
Mastermind-like protein 1 is a protein that in humans is encoded by the MAML1 gene.This protein is the human homolog of mastermind a Drosophila protein that plays a role in the Notch signaling pathway involved in cell-fate determination. There is in vitro evidence that the human homolog forms a complex with the intracellular portion of human Notch receptors and can increase expression of a Notch-induced gene.