Tags: Protein.

Cytoskeleton-associated protein 5 is a microtubule-associated protein that in humans is encoded by the CKAP5 gene. It is the homolog of the Xenopus protein XMAP215 and is also known as ch-Tog.It has at least two distinct roles in spindle formation: it protects kinetochore microtubules from depolymerization by MCAK (KIF2C) and ch-Tog plays an essential role in centrosomal microtubule assembly a function independent of MCAK activity.

Loading...

This page contains content from the copyrighted Wikipedia article "CKAP5"; that content is used under the GNU Free Documentation License (GFDL). You may redistribute it, verbatim or modified, providing that you comply with the terms of the GFDL.