Tags: Enzyme.
Hypoxia-inducible factor-asparagine dioxygenase (EC 1.14.11.30 HIF hydroxylase) is an enzyme with system name hypoxia-inducible factor-L-asparagine 2-oxoglutarate:oxygen oxidoreductase (4-hydroxylating). This enzyme catalyses the following chemical reaction hypoxia-inducible factor-L-asparagine + 2-oxoglutarate + O2 hypoxia-inducible factor-(3S)-3-hydroxy-L-asparagine + succinate + CO2Hypoxia-inducible factor-asparagine dioxygenase contains iron and requires ascorbate.