Tags: Protein.
HLA class II histocompatibility antigen DO beta chain is a protein that in humans is encoded by the HLA-DOB gene.HLA-DOB belongs to the HLA class II beta chain paralogues. This class II molecule is a heterodimer consisting of an alpha (DOA) and a beta chain (DOB) both anchored in the membrane. It is located in intracellular vesicles. DO suppresses peptide loading of MHC class II molecules by inhibiting HLA-DM.