Tags: Chemical Compound, Chemical Substance.
Cyclochlorotine (CC) is a secondary metabolite of the fungus Penicillium islandicum that causes hepatic necrosis and has carcinogenic properties. It is listed as an IARC Group 3 carcinogen.Chemically it is a chlorinated macrocyclic pentapeptide derived from the amino acids 3-phenyl-β-alanine serine dichloroproline and aminobutyric acid.Although tributyltin (TBT) was recently found to induce apoptosis in different immune cells.
