Tags: Drug.

Colistin (polymyxin E) is a polymyxin antibiotic produced by certain strains of Bacillus polymyxa var. colistinus. Colistin is a mixture of cyclic polypeptides colistin A and B. Colistin is effective against most Gram-negative bacilli and is used as a polypeptide antibiotic.Colistin is a decades-old drug that fell out of favor due to its nephrotoxicity. It remains one of the last-resort antibiotics for multidrug-resistant Pseudomonas aeruginosa Klebsiella pneumoniae and Acinetobacter.

Colistin.svg
ATC prefix
A07
ATC suffix
AA10
Bioavailability
0.0
CAS number
1264-72-8
DrugBank
DB00803
FDA UNII code
WP15DXU577
IUPAC name
N-(4-amino-1-(1-(4-amino-1-oxo-1-(31223-tris(2-aminoethyl)- 20-(1-hydroxyethyl)-69-diisobutyl-25811141922-heptaoxo- 147101318-hexaazacyclotricosan-15-ylamino)butan-2-ylamino)- 3-hydroxybutan-2-ylamino)-1-oxobutan-2-yl)-N5-dimethylheptanamide
PubChem
5311054

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