Tags: Drug.

Bacitracin is a mixture of related cyclic polypeptides produced by organisms of the licheniformis group of Bacillus subtilis var Tracy first isolated in 1945. These peptides disrupt both gram positive and gram negative bacteria by interfering with cell wall and peptidoglycan synthesis.Bacitracin is used as a topical preparation (since it is toxic and has poor oral bioavailability).

Bacitracin_A.svg
ATC prefix
D06
ATC suffix
AX05
CAS number
1405-87-4
DrugBank
DB00626
FDA UNII code
58H6RWO52I
IUPAC name
(4R)-4-[(2S)-2-(2-[(1S)-1-amino-2-methylbutyl]- 45-dihydro-13-thiazol-5-ylformamido)-4-methylpentanamido]-4-[(1S)- 1-[(3S6R9S12R15S18R21S)- 18-(3-aminopropyl)-12-benzyl-15-(butan-2-yl)-3-(carbamoylmethyl)- 6-(carboxymethyl)-9-(1H-imidazol-5-ylmethyl)-25811141720- heptaoxo-14710131619-heptaazacyclopentacosan-21-yl]carbamoyl- 2-methylbutyl]carbamoylbutanoic acid
PubChem
439542

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