CD32 is a surface receptor protein and part of a large population of B cell co-receptors which act to modulate signaling.It has a low-affinity for IgG antibodies and down-regulates antibody production in the presence of IgG. This feedback loops essentially lowers the production of IgG produced by B cells when there is a surplus in the body.Monoclonal antibodies can distinguish between CD32A and CD32B.
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