Atrasentan is an experimental drug that is being studied for the treatment of various types of cancer including non-small cell lung cancer.It is an endothelin receptor antagonist selective for subtype […]
List of articles in "Drug" category - Page 283
Atiprimod
Atiprimod (INN codenamed SK&F106615) is a substance being studied in the treatment of certain multiple myelomas and other advanced cancers. It may block the growth of tumors and the growth […]
Atamestane
Atamestane is an aromatase inhibitor that is being studied in the treatment of cancer. Atamestane blocks the production of the hormone estrogen in the body.It is selective.
Tezosentan
Tezosentan is a non-selective ETA and ETB receptor antagonist. It acts as a vasodilator and was designed as a therapy for patients with acute heart failure. Recent studies have shown […]
Ibudilast
Ibudilast (development codes: AV-411 or MN-166) is an antiinflammatory drug used mainly in Japan which acts as a phosphodiesterase inhibitor inhibiting the PDE-4 subtype to the greatest extent but also […]
Proglumide
Proglumide (Milid) is a drug that inhibits gastrointestinal motility and reduces gastric secretions. It acts as a cholecystokinin antagonist which blocks both the CCKA and CCKB subtypes. It was used […]
Amrubicin
Amrubicin (INN; previously known as SM-5887) is an anthracycline used in the treatment of lung cancer. It is marketed in Japan since 2002 by Sumitomo Pharmaceuticals under the brand name […]
Imexon
Imexon (INN trade name Amplimexon) is a substance that is being studied in the treatment of some types of cancer including pancreatic lung breast prostate melanoma and multiple myeloma. It […]
Amonafide
Amonafide (originally AS1413) (INN trade name Quinamed) is a drug that is being studied in the treatment of cancer. It belongs to the families of drugs called topoisomerase inhibitors and […]
Lapaquistat
Lapaquistat (TAK-475) is a cholesterol-lowering drug. Unlike statins which inhibit HMG-CoA reductase lapaquistat metabolites inhibit squalene synthase which is further downstream in the synthesis of cholesterol.