Tags: Drug.

Lapaquistat (TAK-475) is a cholesterol-lowering drug. Unlike statins which inhibit HMG-CoA reductase lapaquistat metabolites inhibit squalene synthase which is further downstream in the synthesis of cholesterol.

Lapaquistat.svg
ATC prefix
none
CAS number
189059-71-0
FDA UNII code
PEZ79BV72X
IUPAC name
(1-[(3R5S)-7-chloro-5-(23-dimethoxyphenyl)-1-(3-hydroxy-22-dimethylpropyl)-2-oxo-1235-tetrahydro-41-benzoxazepin-3-yl]acetylpiperidin-4-yl)acetic acid
PubChem
9960389

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