List of articles in "Drug" category - Page 191

Bupranolol is a non-selective beta blocker without intrinsic sympathomimetic activity (ISA) but with strong membrane stabilizing activity. Its potency is similar to propranolol.

SB-699551 is a drug which was the first compound developed to act as a selective antagonist for the serotonin receptor 5-HT5A with selectivity of around 100x over other serotonin receptor […]

YM-348 is an indazole derivative drug which acts as a potent and selective 5-HT2C receptor agonist with an EC50 of 1nM and 15x selectivity over 5-HT2A although it only has […]

A-372159 is a drug which acts as a potent and selective partial agonist for the 5HT2C receptor with more than 100x selectivity over the closely related 5-HT2B receptor and a […]

AR-A000002 is a drug which is one of the first compounds developed to act as a selective antagonist for the serotonin receptor 5-HT1B with approximately 10x selectivity for 5-HT1B over […]

Manifaxine (GW-320659) is a drug developed by GlaxoSmithKline through structural modification of radafaxine the active metabolite of bupropion. It acts as a norepinephrine-dopamine reuptake inhibitor (NDRI). It was researched for […]

Otenabant (CP-945598) is a drug which acts as a potent and highly selective CB1 antagonist. It was developed by Pfizer for the treatment of obesity but development for this application […]

Prucalopride (brand name Resolor developed by Johnson & Johnson and licensed to Movetis) is a drug acting as a selective high affinity 5-HT4 receptor agonist which targets the impaired motility […]

Dexloxiglumide is a drug which acts as a cholecystokinin antagonist selective for the CCKA subtype.

Devazepide (L-364718 MK-329) is a drug which is structurally derived from the benzodiazepine family but with quite different actions from most benzodiazepines lacking affinity for GABAA receptors and instead acting […]