YM-348 is an indazole derivative drug which acts as a potent and selective 5-HT2C receptor agonist with an EC50 of 1nM and 15x selectivity over 5-HT2A although it only has moderate selectivity of 3x over the closely related 5-HT2B receptor. It has thermogenic and anorectic effects in animal studies making it potentially useful for the treatment of obesity.
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