List of articles in "Drug" category - Page 132

MK-2048 is a second generation integrase inhibitor intended to be used against HIV infection. It is superior to the first available integrase inhibitor raltegravir in that it inhibits the HIV […]

6-Diazo-5-oxo-L-norleucine (DON) is a glutamine antagonist which was isolated originally from Streptomyces in a sample of Peruvian soil. It is a non-standard amino acid. The diazo compound was characterized in […]

JWH-398 is an analgesic chemical from the naphthoylindole family which acts as a cannabinoid agonist at both the CB1 and CB2 receptors. It has mild selectivity for CB1 with a […]

Brentuximab vedotin (INN trade name Adcetris) is an antibody-drug conjugate (ADC) directed to the protein CD30 which is expressed in classical Hodgkin lymphoma (HL) and systemic anaplastic large cell lymphoma […]

Losmapimod (GW856553X) is a drug developed by GlaxoSmithKline which acts as a selective inhibitor of the enzyme family known as p38 mitogen-activated protein kinases.p38 mitogen-activated protein kinases are mediators of […]

For more information about this drug and its actions see combretastatin.Combretastatin A-4 phosphate (fosbretabulin and its salt fosbretabulin disodium) is a microtubule destabilizing drug a type of vascular-targeting agent a […]

Veliparib (ABT-888) is a potential anti-cancer drug acting as a PARP inhibitor. It kills cancer cells by blocking a protein called PARP thereby preventing the repair of DNA or genetic […]

Tiamulin is a pleuromutilin antibiotic drug that is used in veterinary medicine particularly for pigs and poultry.Tiamulin is a diterpene antimicrobial with a pleuromutilin chemical structure similar to that of […]

Fidaxomicin (trade names Dificid Dificlir and previously OPT-80 and PAR-101) is the first in a new class of narrow spectrum macrocyclic antibiotic drugs. It is a fermentation product obtained from […]

LY-487379 is a drug used in scientific research that acts as a selective positive allosteric modulator for the metabotropic glutamate receptor group II subtype mGluR2. It is used to study […]