Tags: Drug.
For more information about this drug and its actions see combretastatin.Combretastatin A-4 phosphate (fosbretabulin and its salt fosbretabulin disodium) is a microtubule destabilizing drug a type of vascular-targeting agent a drug designed to damage the vasculature (blood vessels) of cancer tumors causing central necrosis. It is a derivative of combretastatin.Combretastatin A-4 phosphate is a prodrug. In vivo it is dephosphorylated to its active metabolite combretastatin A-4.
