Tags: Protein.
C1 domain (also known as phorbol esters/diacylglycerol binding domain) binds an important secondary messenger diacylglycerol (DAG) as well as the analogous phorbol esters. Phorbol esters can directly stimulate protein kinase C PKC. The N-terminal region of PKC known as C1 has been shownPhorbol esters (such as PMA) are analogues of DAG and potent tumor promoters that cause a variety of physiological changes when administered to both cells and tissues.
