Tags: Enzyme.
Hydroxyprostaglandin dehydrogenase 15-(NAD) (the HUGO-approved symbol = HPGD; HGNC ID HGNC:5154) also called 15-hydroxyprostaglandin dehydrogenase (NAD+) (EC 1.1.1.141) is an enzyme that catalyzes the chemical reaction(5Z13E)-(15S)-11alpha15-dihydroxy-9-oxoprost-13-enoate + NAD+ (5Z13E)-11alpha-hydroxy-915-dioxoprost-13-enoate + NADH + H+Thus the two substrates of this enzyme are (5Z13E)-(15S)-11alpha15-dihydroxy-9-oxoprost-13-enoate and NAD+ whereas its 3 products are (5Z13E)-11alpha-hydroxy-915-dioxoprost-13-enoate NADH and H+.This enzyme belongs to the family of oxidoreductases specifically those acting on the CH-OH group of donor with NAD+ or NADP+ as acceptor.