Tags: Chemical Compound, Chemical Substance.
Zymosan is a glucan with repeating glucose units connected by β-13-glycosidic linkages. It binds to TLR 2. Zymosan is a ligand found on the surface of fungi like yeast. Zymosan is prepared from yeast cell wall and consists of protein-carbohydrate complexes. It is used to induce experimental sterile inflammation. In macrophages zymosan-induced responses include the induction of proinflammatory cytokines arachidonate mobilization protein phosphorylation and inositol phosphate formation.
