Tags: Drug.

Zotarolimus (INN codenamed ABT-578) is an immunosuppressant. It is a semi-synthetic derivative of rapamycin. It was designed for use in stents with phosphorylcholine as a carrier. Coronary stents reduce early complications and improve late clinical outcomes in patients needing interventional cardiology. The first human coronary stent implantation was first performed in 1986 by Puel et al.

Zotarolimus.png
ATC prefix
none
CAS number
221877-54-9
FDA UNII code
H4GXR80IZE
IUPAC name
(3S6R7E9R10R12R14S15E17E19E21S23S26R27R34aS)-927-dihydroxy-1021-dimethoxy-3-(1R)-2-[(1S3R4S)-3-methoxy-4-(1H-tetrazol-1-yl)cyclohexyl]-1-methylethyl)-6812142026-hexamethyl-49101213142122232425262732333434a-heptadecahydro-3H-2327-epoxypyrido[21-c][14]oxazacyclohentriacontine-15112829(6H31H)-pentone

Loading...

This page contains content from the copyrighted Wikipedia article "Zotarolimus"; that content is used under the GNU Free Documentation License (GFDL). You may redistribute it, verbatim or modified, providing that you comply with the terms of the GFDL.