Tags: Disease.
Zollinger–Ellison Syndrome (ZES) is caused by a non–beta islet cell gastrin-secreting tumor of the pancreas that stimulates the acid-secreting cells of the stomach to maximal activity with consequent gastrointestinal mucosal ulceration. ZES may occur sporadically or as part of an autosomal dominant familial syndrome called multiple endocrine neoplasia type 1 (MEN 1).
