Tags: Protein.
ZIC1 is a member of the Zinc finger of the cerebellum (ZIC) protein family.ZIC1 is classified as a ZIC protein due to conservation of the five C2H2 zinc fingers which enables the protein to interact with DNA and proteins. ZIC1 is found in close genomic configuration in another member of this protein family ZIC4. Correct function of these proteins in critical for early development and as such mutations of the genes encoding these proteins is known to result in various congenital defects.