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X-linked reticulate pigmentary disorder (also known as Familial cutaneous amyloidosis Partington amyloidosis Partington cutaneous amyloidosis Partington syndrome type II Reticulate pigmentary disorder and X-linked reticulate pigmentary disorder with systemic manifestations) is a cutaneous condition that has been described in adult women that had linear streaks of hyperpigmentation and in which male patients manifested a reticulated mottled brown pigmentation of the skin which on biopsy demonstrated dermal deposits of amyloid.The syndrome is also referred with the acronym X-Linked-PDR or even XLPRD.It’s a very rare disease genetically determined with a chronic course.

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